Notre Dame fell 69-68 to St. John's as Tory Jackson missed two three-pointers in the final seconds.
Jackson wasn't the Irish's first option as a shooter in the final seconds as he went 1 for 10 in the loss.
"With 12 seconds left and no timeouts, you are not running anything," Irish coach Mike Brey said. "The best offense we had was post feed to Ty Nash. There wasn't enough time to do that.
"We had to get a driving area. I thought (Jackson) could drive it there, but I thought they took that away. You got to get something going to the basket, and they kind of took that away. I thought Tory could get in there and kick to a shooter, but he couldn't get in there."
Jackson, who scored a career-high 25 points in Thursday's loss to Seton Hall, said he should have found a teammate to take that shot as the clock wound down.
"I should have went to T-Nash (forward Tyrone Nash), he was the one feeling it, him and Abro (Tim Abromaitis)," Jackson said. "That was just selfish of me, and I'm not that type of guy. I'm going to clear that up."
Abromaitis gave the Irish (17-9, 6-7 Big East) a 66-64 lead with 1:25 to play when he hit a three-pointer from the left corner.
Abromaitis' three came on the heels of his old-fashion three-point play when he sank a free-throw after getting fouled on a baseline dunk.
After St. John's took a 67-66 lead with a three with 56 seconds to play, Nash did his best Luke Harangody impersonation.
Nash drew a foul on the left block and sank two free throws for a 68-67 lead with 38.9 to play. Harangody did not play Sunday because of a bruised bone on his right knee.
But St. John's (14-10, 4-8) took the lead back with a pair of free throws from D.J. Kennedy with 12.5 to play.
Abromaitis finished wit 24 points, and Nash had 16.
Brey said Harangody will be day-to-day this week, but the coach doesn't expect Harangody to play Wednesday at Louisville.
"We have to prepare like he's not going to play and use the week to get him back," Brey said.
Notre Dame has lost its last two games, and at 6-7 in the conference, the Irish's chances of reaching the NCAA tournament are shrinking.
Notre Dame, which is 1-5 on the road in Big East play, has five games remaining this season. Three of those games are on the road (at Louisville on Wednesday; at Georgetown Feb. 27 and at Marquette on March 3).
The two home games are against Pittsburgh on Feb. 24, and Connecticut on March 3.
With only Connecticut struggling more than Notre Dame right now, the Irish are likely heading towards another year out of the NCAA and in the NIT.