Notre Dame forward Erica Williamson scored 16 points as five Irish players scored in double figures in an 89-52 route of Louisville in the second round of the Big East tournament in Hartford, Conn.
Skyler Diggins had 13 points, Deveraux Peters added 11, and Lindsay Schrader and Becca Bruszewski each had 10. The No. 6 Irish (26-4) will play No. 16 St. John's in the quarterfinals on Sunday.
The Irish and Red Storm finished the regular season tied for fourth place in the league, but St. John's earned the double bye with a 76-71 win over Notre Dame on Feb. 16.
"We are really looking forward, if we win our first game, to playing St. John's," Williamson said in a phone interview Thursday. "I think we all feel like we deserve a little bit of payback. We didn't think we played very well when we played them the first time."