Patently Speaking highlights the technological achievements of Fort Wayne-area residents.
Chemical treatment for removing cellular and nuclear material from naturally occurring extracellular matrix-based biomaterials
U.S. Patent No. 7,763,459
Invented by: Prasanna Malaviya, Fort Wayne; Rangamani Padmini, New York; and Janine Orban, Warsaw
Small intestine submucosa is a remarkable medicinal material. It comes from the small intestine and is used to regenerate all sorts of human tissue – from tendons to cartilage. Sheets of this SIS applied to a wound gradually heal the damaged area.
Conventional SIS works well but may include impurities like non-viable nucleic acids that can leach out during the tissue regeneration process.
This has been treated in the past by using washes of ethanol and peracetic acid. These washes remove the nucleic acids, but they can also adversely affect the mechanical properties of SIS.
This patent describes a new process for removing nucleic acids by using a series of extraction steps. The first step involves treating the material with a first solubilizing fluid such as hydrogen peroxide.
After that, a second solubilizing treatment is performed using both first and second solubilizing fluids. The second solubilizing fluid is peracetic acid. Part of this process is ensuring that the first and second solubilizing fluids are different.
Lastly, the material is then washed using distilled water to remove any debris.
Insertion die tooling for flange installation and the method of use
U.S. Patent No. 7,591,054
Invented by: Gary M. Baughman, Fremont
Assigned to Rieke Corp., Auburn
This patent describes a new way of making a metal container or drum lid.
A steel container includes a cylindrical wall that is attached to a lid and a base. Such drums require an opening at the top so the liquid inside can be poured or siphoned out. Typically, these openings are threaded to receive a corresponding threaded cap.
This patent describes a press that attaches a threaded flange to the lid. The flange includes the threaded opening to which the cap attaches.
The press includes a frusto-conical pilot that presses the metal lid around the threaded flange. Frusto-conical means cone-shaped with the point of the cone sliced off.
Collets press against the outside of the lid and flange connecting the two together, forming the completed lid.
The preceding are lay descriptions of patents obtained from the United States Patent and Trademark Offices public records and are provided for general information purposes only. Nothing contained herein is a legal description of any claimed invention, identification of novelty, or offer of legal advice.
Because issued patents are based on applications often filed years earlier, the subject matter of some patents may have been available on the market for some time prior to the issuance of the patent. Additional information on these patents is available at www.uspto.gov.