Purdue and Nebraska meet for the first time since 1979.
The Boilermakers (17-10, 7-7 Big Ten) could use the win as they continue to build their resume for the postseason.
D.J. Byrd should be back in action after serving a one-game suspension for violating team rules.
Nebraska's Bo Spencer is averaging 15.5 points and 3.4 assists per game.
The Cornhuskers (12-13, 4-10) snapped a four-game losing streak last week with a win against Illinois.