Adys Portillo's no-hit bid came to an end in the seventh inning as Matt Helm doubled with one out in the inning.
Portillo has displayed a sharp breaking ball to go along with an overpowering fastball Wednesday.
He has six strikeouts. The right-hander, who entered the game with a 1.72 ERA, has walked two batters.
The TinCaps have a 5-0 lead.