The U.S. House voted Wednesday afternoon to repeal President Obama’s health care law.

The Republican-controlled House voted 244-185, largely along party lines. The Democratic Senate is not expected to consider the repeal legislation.

“This is the largest tax increase in American history and, if Congress doesn’t act, the health care law will hurt families and small businesses during the weakest recovery since the Great Depression,” Rep. Marlin Stutzman, R-3rd, said in a statement after voting in favor of the repeal.

The Supreme Court on June 28 issued a ruling that upheld the Patient Protection and Affordable Care Act, which Obama signed into law in 2010 after it was passed by a Democratic House and Senate.

Stutzman said the law “puts unelected bureaucrats, like the Independent Payment Advisory Board, between patients and their doctors. Americans deserve choices, not top-down controls.”

Reps. Dan Burton, R-5th, and Mike Pence, R-6th, the GOP candidate for governor of Indiana, also voted in favor of repealing the Affordable Care Act.

Rep. Joe Donnelly, D-2nd, the Democratic candidate for a Senate seat from Indiana, voted against the repeal.

“The health care law includes good provisions that are already helping Hoosiers,” Donnelly said in a statement. “Seniors are paying less for prescription drugs and children with preexisting conditions like diabetes and rheumatoid arthritis now have health coverage for the first time. Repealing the health care law would undo these benefits and negatively impact millions of lives across the country.”

Donnelly said he remains opposed to the law’s 2.3 percent tax on medical device sales. Stutzman said the tax threatens 2,000 jobs in Indiana, where more than 21,000 people work for companies that manufacture medical devices.

Wednesday’s vote was the 31st time the House has voted to repeal all or parts of the Affordable Care Act.