INDIANAPOLIS – Andrew Luck is getting a crash course in rematch etiquette.

The man who seemingly did it all in college never played the same team twice in one season until he jumped to the NFL. On Sunday, he’ll get a second chance at a second chance when Tennessee (4-8) visits Lucas Oil Stadium.

“It’s different,” the rookie quarterback said, referring to his preparation for his second game against Jacksonville on Nov. 8. “It’s interesting when you go back and watch before.”

Like his successor, Peyton Manning, Luck spends most of his time scouring game film for a couple of things: Mistakes and finding ways to beat defenses.

Luck is hardly alone in the film room. With one of the NFL’s youngest teams, the Colts (8-4) have one of the most studious rookie classes, too.

Indianapolis drafted tight ends Coby Fleener and Dwayne Allen in the second and third rounds, receivers T.Y. Hilton and LaVon Brazill in the third and sixth rounds and running back Vick Ballard in the fifth round.

Each has had a major hand in this season’s turnaround from 2-14. Brazill and Fleener each caught a touchdown pass in Sunday’s comeback at Detroit, Hilton has already had four 100-yard games, Allen needs seven catches in the final four games to set the Colts’ rookie record for receptions by a tight end and it was Ballard’s backward, twisting flip that gave the Colts their first road win of the season at Tennessee on Oct. 28.

In the first contest against Tennessee, Luck was 26 of 38 for 297 yards with one touchdown and one interception. Indianapolis also rushed for a season-high 171 yards and Ballard’s highlight-making dive won the game in overtime.

Notes: Interim head coach Bruce Arians said running back Donald Brown and safety Tom Zbikowski would both miss Sunday’s game because of undisclosed knee injuries. ... Sunday’s game is sold out and will be televised locally. ... Head coach Chuck Pagano has finished his third and final round of chemotherapy, but it is still uncertain whether he will attend his third straight home game. Pagano has been on an indefinite leave since being diagnosed with leukemia Sept. 26. ... The Colts signed linebacker Jamaal Westerman to the active roster, activated offensive guard Seth Olsen from injured reserve and have placed linebacker Justin Hickman on injured reserve.