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Week 3

Indianapolis at San Francisco

Time: 4:25 p.m. (CBS)

Records: Colts (1-1), 49ers (1-1)

The skinny: The 49ers will be glad to get back home and hear their signals again after playing in Seattle. Colin Kaepernick might be glad to be home where he is 5-0 as a starter. And Coach Jim Harbaugh might be glad to see the quarterback he coached at Stanford, Andrew Luck. But the Colts might not be glad to see the 49ers.

Prediction: 49ers, 34-21

Chicago at Pittsburgh

Time: 8:30 p.m. (NBC)

Records: Bears (2-0), Steelers (0-2)

The skinny: The Bears have come done something in their first two games that the Steelers have had trouble doing – finding ways to win. They came back in the final minutes against the Bengals and Vikings to remain unbeaten. Conversely, the Steelers haven’t scored enough points (19) to be able to come back against anyone.

Prediction: Bears, 23-20

Houston at Baltimore

Time: 1 p.m. (CBS)

Records: Texans (2-0), Ravens (1-1)

The skinny: The Texans are the first team since the 1970 merger to win their first two games on the final play. The Ravens have never lost at home to the Texans (3-0).

Prediction: Texans, 24-20

Green Bay at Cincinnati

Time: 1 p.m. (Fox)

Records: Packers (1-1), Bengals (1-1)

The skinny: The Packers became the first team in NFL history to have a 450+-yard passer (Aaron Rodgers) and a 125+-yard rusher (James Starks) in the same game, proof that the pass can indeed be used to set up the run.

Prediction: Packers, 30-24

N.Y. Giants at Carolina

Time: 1 p.m.

Records: Giants (0-2), Panthers (0-2)

The skinny: Eli Manning has thrown seven interceptions in the first two games. But he is going to need more help from his defense, which has given up a league-high 77 points. The Panthers aren’t feeling like a winless team after close losses to the Seahawks and Bills.

Prediction: Giants, 23-21

St. Louis at Dallas

Time: 1 p.m.

Records: Rams (1-1), Cowboys (1-1)

The skinny: The Rams’ Tavon Ausleads all rookies with 12 catches, including two TDs last week. But the Cowboys are glad to see Dez Bryant back involved in their passing game.

Prediction: Cowboys, 27-23

Cleveland at Minnesota

Time: 1 p.m.

Records: Browns (0-2), Vikings (0-2)

The skinny: The Browns have managed just 16 points in two games. The Vikings have produced lots of points in two games (54). Their problem has been preventing them (65).

Prediction: Vikings, 23-17

Tampa Bay at New England

Time: 1 p.m.

Records: Buccaneers (0-2), Patriots (2-0)

The skinny: Typically, cornerback Darrelle Revis might have to worry about facing the Patriots in New England. But have you checked the receivers Tom Brady has to work with now?

Prediction: Patriots, 24-14

Arizona at New Orleans

Time: 1 p.m.

Records: Cardinals (1-1), Saints (2-0)

The skinny: Cardinals CB Patrick Peterson had four tackles and a pass defense against the Lions, he caught a 17-yard pass and had a 17-yard completion – the first defender since 1970 to have a catch and completion in same game. They will need some of that in the Superdome.

Prediction: Saints, 30-23

San Diego at Tennessee

Time: 1 p.m.

Records: Chargers (1-1), Titans (1-1)

The skinny: Both teams have lost to the Texans and both are immediately better than what people expected. The Titans came within an overtime period against the Texans of being 2-0 for their first home game. And the Chargers blew a 21-point lead to the Texans or they would be unbeaten.

Prediction: Chargers, 24-23

Detroit at Washington

Time: 1 p.m.

Records: Lions (1-1), Redskins (0-2)

The skinny: Panic is setting with the Redskins, who have given up 71 points in two games and are worried about RG3.

Prediction: Redskins, 26-21

Atlanta at Miami

Time: 4:05 p.m.

Records: Falcons (1-1), Dolphins (2-0)

The skinny: The Dolphins have already won back-to-back road games to start the season and have done it with a pass rush that has produced nine sacks.

Prediction: Dolphins, 27-24

Buffalo at N.Y. Jets

Time: 4:25 p.m.

Records: Bills (1-1), Jets (1-1)

The skinny: E.J. Manuel and Geno Smith have each thrown game-winning TD passes in the final two minutes this season.

Prediction: Jets, 17-16

Jacksonville at Seattle

Time: 4:25 p.m.

Records: Jaguars (0-2), Seahawks (2-0)

The skinny: The Jaguars have managed a league-low 11 points in two games. Playing in the noise in Seattle only makes it worse. The Seahawks did not lose at home last season and it doesn’t appear that will change this season, not after the way they manhandled the 49ers.

Prediction: Seahawks, 30-0

Oakland at Denver

Time: 8:40 p.m. Monday (ESPN)

Records: Raiders (1-1), Broncos (2-0)

The skinny: Peyton Manning has thrown nine touchdowns and has never lost to an AFC West team (6-0) since joining the Broncos.

Prediction: Broncos, 35-17

– Gerry Dulac, Pittsburgh Post-Gazette Record: 12-4 last week (22-10 overall, does not include Thursday games)