SOUTH BEND – Notre Dame gave too much away to Oklahoma as it went into halftime trailing 21-7.
The No. 14 Sooners scored all of their points off turnovers by the No. 22 Irish.
Oklahoma scored two touchdowns in the game's opening 2:45 with an interception return for a score and another interception setting up a four-play scoring drive.
The Sooners scored the only points of the second quarter thanks to Julian Wilson intercepting a tipped pass with 5:25 to play in the opening half. Wilson also had a first-quarter interception that set up Oklahoma's second touchdown.
Oklahoma converted on two third down plays on the drive after Wilson's second interception, and quarterback Blake Bell ended the drive with a 26-yard touchdown pass to Lacolton Bester with 42 seconds to play in the first half.
The Irish took two knees after the Bester touchdown to go into the break down by 14.
Notre Dame has kept pace with Oklahoma on offense as the Sooners only hold a 190-164 advantage in yards.
But the three interceptions by Tommy Rees, who is 6 for 13 for 52 yards, has been the difference.
Oklahoma quarterback Blake Bell is 12 for 16 for 102 yards with a touchdown.
The Irish have mixed in quarterback Andrew Hendrix in the offense to help boost their running game.
Hendrix along with running backs Amir Carlisle, Cam McDaniel, George Atkinson III and Tarean Folston have combined to run for 112 yards on 20 rushing attempts. Notre Dame had not run for at least 100 yards since the season-opening win against Temple.