Robert Johnson's 3-pointer hit off the rim as time expired, and Indiana lost a back-and-forth contest at Maryland in its first Big Ten road game of the season.
Melo Trimble scored 18 points and Anthony Cowan 15 as the Terrapins held on for a 75-72 win Tuesday night at the Xfinity Center in College Park, Maryland.
The Hoosiers (11-6, 1-3) pulled within 73-72 on a dunk by OG Anunoby and intentionally fouled Trimble, who made both free throws with 8.2 seconds left to force Indiana into needing a 3-pointer to reach overtime.
Former Bishop Luers star James Blackmon Jr. had 22 points to become the 50th player in IU history to reach the career 1,000-point mark.
Cowan's breakaway layup put the Terrapins ahead 73-70 with 1:13 left. Center Damonte Dodd gave them six points, six rebounds and six blocked shots.
Maryland (15-2, 3-1) shot 44 percent to the Hoosiers' 42 percent in a game which featured nine ties and 15 lead changes.
Kevin Huerter's catch-and-shoot 3-pointer from the left wing capped Maryland's 7-0 run for a 66-63 lead, but Blackmon responded by driving by Huerter for a basket and then drilling a 3 over Huerter's outstretched arms to give Indiana a 68-66 edge entering a timeout with 3:28 to play.
Dodd's putback tied it at 68, and after Indiana came up empty on the ensuing possession, Dodd committed a loose-ball foul that put Juwan Morgan on the free-throw line. Morgan made both for a 70-68 edge with 2:03 showing.
At 1:46, Huerter (11 points, seven rebounds) connected on another 3 to give Maryland the lead for good.
A 7-0 run had provided the Hoosiers a 47-43 lead with 16 minutes to play, their largest advantage to that point. Johnson finished with 13 points.
The Hoosiers wore their special uniforms from the season opener at the Armed Forces Classic, with "Courage" inscribed on the back to honor members of the military. In a pregame press release, the Hoosiers said the jerseys were brought back because they were "playing so close to our nation’s capitol."
The Terrapins said center Michal Cekovsky, averaging 10 points per game, sat out because of an injured left ankle.